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A recent case report describes an extremely rare solitary fibrous tumor (SFT) occurring in the maxilla (upper jaw), highlighting the importance of accurate diagnosis in rare soft tissue tumors. Although SFT is different from synovial sarcoma, both are rare mesenchymal tumors that can present similarly, making diagnosis dependent on specialized testing. A Rare Presentation A […]
Most synovial sarcoma tumors develop in the soft tissues near the joints of the arms or legs in adolescents and young adults. However, physicians occasionally encounter rare presentations in other organs. A recent case report describes primary synovial sarcoma of the lung in a young child, highlighting how difficult rare pediatric sarcomas can be to […]
Synovial sarcoma is a rare soft tissue sarcoma most commonly treated with surgery, chemotherapy, radiation therapy, and targeted drugs such as pazopanib. However, treatment options can be limited for advanced or metastatic disease. A recently published case report describes a patient with synovial sarcoma who achieved a complete response after receiving targeted therapy based on […]
On February 19, 2026, the Synovial Sarcoma Foundation brought together patients, families, clinicians, and researchers from around the world for its second community webinar—an evening focused on progress, partnership, and hope. The full webinar recording is available to watch below: The webinar was moderated by Nathan Imperiale, Chairman of the Board, and featured: Highlights Foundation […]
Synovial sarcoma is driven by a defining genetic event — the SS18-SSX fusion protein, present in nearly all cases. For years, research and therapeutic development have focused on how this fusion interacts with the SWI/SNF chromatin remodeling complex, believed to play a central role in tumor growth. However, newly published research challenges that long-standing assumption […]
Join the Synovial Sarcoma Foundation for a live, one-hour webinar focused on where synovial sarcoma research is heading and what that progress means for patients and families today. The conversation will bring together real patient experiences with insights from researchers and clinicians leading efforts in synovial sarcoma. We’ll discuss emerging research, areas of real momentum, […]
Content Warning:This article references a published medical case study that includes graphic surgical images involving the head and neck region. While the information may be valuable and informative, some readers may find the images difficult to view. Please proceed with care. Synovial sarcoma most often develops in the extremities, but in rare cases, it can […]
The Synovial Sarcoma Foundation is excited to share that we are on site this week at the 2025 Connective Tissue Oncology Society (CTOS) Annual Meeting in Boca Raton, Florida. This global event brings together leading researchers, oncologists, and experts in sarcoma to discuss the latest data-driven advancements in diagnosis, treatment, and clinical trials. Representing our Board of […]
Not every detected cancer is clinically meaningful. For younger patients, especially, this can mean confronting a diagnosis that may never progress but still carries psychological and treatment burdens.
