Our Chairman of the Board of Directors, Nathan Imperiale, was recently invited by Philip Leider, President of the Board of the Sarcoma Alliance, to present about the Synovial Sarcoma Foundation in a live webinar hosted by the Sarcoma Alliance. The conversation covered the Foundation’s origin…
Synovial Sarcoma of the Hyoid Bone: A Rare Case
A case report by Ryan Toledo, Jennifer Khong, and colleagues (published August 31, 2026; DOI: 10.7812/TPP/26.039) describes only the third known synovial sarcoma arising from the hyoid bone, a small U-shaped bone in the neck. The patient, a 62-year-old man, remains disease-free years after treatment.…
Two clinical trials testing TCR-NK cell therapy for advanced synovial sarcoma are now recruiting patients, one in the United States and one in the United Kingdom. Both use donor-derived natural killer cells engineered to target proteins commonly found on synovial sarcoma tumors. What Is TCR-NK…
What a Breakthrough in Ewing Sarcoma Means for Synovial Sarcoma
A new Phase 1/2 trial in Ewing sarcoma, just profiled in Clinical Trial Vanguard and published in Nature Medicine, delivered…
Rare Tumor Mimics Synovial Sarcoma: Why Accurate Diagnosis Matters
A recent case report highlights a rare GLI1-altered mesenchymal tumor presenting in the pleura (lining of the lung), a location…
Cell Therapies for Synovial Sarcoma: Afami-cel (Tecelra)
Advances in cell therapy for synovial sarcoma are creating more treatment options for patients with advanced disease. A recent update…
Synovial Sarcoma Around the Heart: Rare Case Highlights Importance of Early Diagnosis
Synovial sarcoma is a rare soft tissue cancer that usually develops near joints in the arms or legs. However, in…
Primary Cardiac Synovial Sarcoma: A Rare and Challenging Diagnosis
Synovial sarcoma is a rare soft tissue cancer that most commonly develops near the joints of the arms or legs.…
Post-Surgical Complication in Synovial Sarcoma: Rare Case Highlights Pleural Aspergillosis Risk
A recent case report describes a rare but serious complication in a patient with metastatic synovial sarcoma of the lung—highlighting…
Rare Tumor Case Highlights Importance of Accurate Diagnosis in Sarcoma Care
A recent case report describes an extremely rare solitary fibrous tumor (SFT) occurring in the maxilla (upper jaw), highlighting the…
Rare Disease Drug Development and Synovial Sarcoma: Why Funding Still Falls Short
A recent BioSpace article highlights a critical challenge in rare disease drug development: many promising therapies are not limited by…
Synovial Sarcoma in Children: A Rare Case Affecting the Lung
Most synovial sarcoma tumors develop in the soft tissues near the joints of the arms or legs in adolescents and…
