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    CHOP, Development, Dr. Theodore Laetsch, Research

    Synovial Sarcoma Foundation Celebrates Groundbreaking Achievement by Rachel Dr. Hurly

    June 3, 2025 joshs Comments Off on Synovial Sarcoma Foundation Celebrates Groundbreaking Achievement by Rachel Dr. Hurly
    Close-up of the objective lenses of a microscope, showing three metal lenses labeled with magnification levels above a microscope stage—a vital tool in research supported by the Synovial Sarcoma Foundation.

    Dr. Hurly’s Innovative Work Aims at Improving Therapeutic Options for Patients with Synovial Sarcoma

    Philadelphia, PA — The Synovial Sarcoma Foundation is proud to announce a significant milestone: Dr. Rachel Hurly, a dedicated pediatric oncology fellow from the Children’s Hospital of Philadelphia (CHOP), has been honored with the prestigious American Society of Clinical Oncology (ASCO) Young Investigator Award. Dr. Hurly conducts her research under the mentorship of Dr. Ted Laetsch at the Haldor Laboratory at the University of Pennsylvania, with support from the Synovial Sarcoma Foundation.

    Dr. Hurly’s project focuses on the tumor microenvironment (TME) and its role in enabling or hindering the effectiveness of immunotherapy, specifically investigating the modulation of the TME through the inhibition of retinaldehyde dehydrogenase (RALDH). Early findings suggest that targeting RALDH could promote immune responses against the tumor and enhance the efficacy of existing immunotherapies.

    Chas Spence, Executive Director and Founder of the Synovial Sarcoma Foundation, stated, “Dr. Hurly’s research holds tremendous promise for advancing our understanding of how to manipulate the tumor microenvironment to make immunotherapies more effective for children with synovial sarcoma. Her dedication and innovative approach are truly inspiring.”

    Spence continued, “Our family’s journey with our son Callan’s diagnosis motivated us to become lifelong advocates for synovial sarcoma research. Dr. Hurly’s research and her strong foundation will help propel these efforts forward.”

    The Foundation acknowledges the significant importance of this research, which has the potential to revolutionize the treatment landscape for pediatric sarcoma. The project’s preliminary data highlights promising avenues for future therapeutic development, aiming to improve survival rates and quality of life for young patients.

    “This recognition not only underscores the significance of Dr. Hurly’s research but also emphasizes the vital role that collaborative efforts and dedicated funding play in tackling rare cancers,” added Spence. “We remain committed to supporting groundbreaking research that offers hope and new possibilities for children afflicted by synovial sarcoma and other pediatric cancers.”

    The Synovial Sarcoma Foundation extends its congratulations to Dr. Hurly and her team and remains steadfast in its mission to fund innovative research, foster collaboration, and improve outcomes for pediatric sarcoma patients worldwide.

    About the Synovial Sarcoma Foundation
    The Synovial Sarcoma Foundation is dedicated to funding research, supporting patients and families, and advancing the understanding of synovial sarcoma and related soft tissue sarcomas. Through collaborative efforts, the Foundation aims to accelerate discoveries that lead to more effective treatments and, ultimately, cures.

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    Recent posts

    • Black and white photo of a baby's legs and feet resting on a soft blanket, with the focus on the feet and toes. The background and upper body are blurred.
      Synovial Sarcoma of the Parotid Gland in Infancy: A Rare Case Study
    • Two surgeons wearing surgical masks and caps focus intently on a procedure under bright operating room lights, with another medical professional visible in the background.
      Monophasic Synovial Sarcoma of the Posterior Pharyngeal Wall: A Rare Case Study
    • A gloved hand holds a clear petri dish near a microscope in a bright laboratory setting, suggesting scientific research or experiment.
      UI Health Care Begins Treating Patients With TCR Therapy for Synovial Sarcoma

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    Related posts

    Black and white photo of a baby's legs and feet resting on a soft blanket, with the focus on the feet and toes. The background and upper body are blurred.
    Research, Case Study, Children, Education, Latest News

    Synovial Sarcoma of the Parotid Gland in Infancy: A Rare Case Study

    February 2, 2026 ayushis Comments Off on Synovial Sarcoma of the Parotid Gland in Infancy: A Rare Case Study

    Synovial sarcoma most often develops near the large joints of the arms or legs, but in rare cases it can arise in the head and neck region. An especially uncommon presentation occurs in infants. A recently published case report describes synovial sarcoma originating in the parotid gland—the salivary gland located near the jaw and ear—in […]

    Two surgeons wearing surgical masks and caps focus intently on a procedure under bright operating room lights, with another medical professional visible in the background.
    Healthcare, Education, Research

    Monophasic Synovial Sarcoma of the Posterior Pharyngeal Wall: A Rare Case Study

    January 26, 2026 ayushis Comments Off on Monophasic Synovial Sarcoma of the Posterior Pharyngeal Wall: A Rare Case Study

    Content Warning:This article references a published medical case study that includes graphic surgical images involving the head and neck region. While the information may be valuable and informative, some readers may find the images difficult to view. Please proceed with care. Synovial sarcoma most often develops in the extremities, but in rare cases, it can […]

    A gloved hand holds a clear petri dish near a microscope in a bright laboratory setting, suggesting scientific research or experiment.
    Healthcare, Latest News, Research

    UI Health Care Begins Treating Patients With TCR Therapy for Synovial Sarcoma

    January 21, 2026 ayushis Comments Off on UI Health Care Begins Treating Patients With TCR Therapy for Synovial Sarcoma

    UI Health Care has begun treating eligible patients with synovial sarcoma using a new form of immunotherapy known as T cell receptor (TCR) therapy. This treatment approach represents an important step forward in expanding access to innovative options for people facing advanced synovial sarcoma. A targeted immune-based approach TCR therapy is designed to help the […]

    The Synovial Sarcoma Foundation is a registered 501(c)(3) nonprofit organization. Tax ID number is 33-4027591. Contributions to the Synovial Sarcoma Foundation are tax-deductible to the extent permitted by law.

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