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    CHOP, Development, Dr. Theodore Laetsch, Research

    Synovial Sarcoma Foundation Celebrates Groundbreaking Achievement by Rachel Dr. Hurly

    June 3, 2025 joshs Comments Off on Synovial Sarcoma Foundation Celebrates Groundbreaking Achievement by Rachel Dr. Hurly
    Close-up of the objective lenses of a microscope, showing three metal lenses labeled with magnification levels above a microscope stage—a vital tool in research supported by the Synovial Sarcoma Foundation.

    Dr. Hurly’s Innovative Work Aims at Improving Therapeutic Options for Patients with Synovial Sarcoma

    Philadelphia, PA — The Synovial Sarcoma Foundation is proud to announce a significant milestone: Dr. Rachel Hurly, a dedicated pediatric oncology fellow from the Children’s Hospital of Philadelphia (CHOP), has been honored with the prestigious American Society of Clinical Oncology (ASCO) Young Investigator Award. Dr. Hurly conducts her research under the mentorship of Dr. Ted Laetsch at the Haldor Laboratory at the University of Pennsylvania, with support from the Synovial Sarcoma Foundation.

    Dr. Hurly’s project focuses on the tumor microenvironment (TME) and its role in enabling or hindering the effectiveness of immunotherapy, specifically investigating the modulation of the TME through the inhibition of retinaldehyde dehydrogenase (RALDH). Early findings suggest that targeting RALDH could promote immune responses against the tumor and enhance the efficacy of existing immunotherapies.

    Chas Spence, Executive Director and Founder of the Synovial Sarcoma Foundation, stated, “Dr. Hurly’s research holds tremendous promise for advancing our understanding of how to manipulate the tumor microenvironment to make immunotherapies more effective for children with synovial sarcoma. Her dedication and innovative approach are truly inspiring.”

    Spence continued, “Our family’s journey with our son Callan’s diagnosis motivated us to become lifelong advocates for synovial sarcoma research. Dr. Hurly’s research and her strong foundation will help propel these efforts forward.”

    The Foundation acknowledges the significant importance of this research, which has the potential to revolutionize the treatment landscape for pediatric sarcoma. The project’s preliminary data highlights promising avenues for future therapeutic development, aiming to improve survival rates and quality of life for young patients.

    “This recognition not only underscores the significance of Dr. Hurly’s research but also emphasizes the vital role that collaborative efforts and dedicated funding play in tackling rare cancers,” added Spence. “We remain committed to supporting groundbreaking research that offers hope and new possibilities for children afflicted by synovial sarcoma and other pediatric cancers.”

    The Synovial Sarcoma Foundation extends its congratulations to Dr. Hurly and her team and remains steadfast in its mission to fund innovative research, foster collaboration, and improve outcomes for pediatric sarcoma patients worldwide.

    About the Synovial Sarcoma Foundation
    The Synovial Sarcoma Foundation is dedicated to funding research, supporting patients and families, and advancing the understanding of synovial sarcoma and related soft tissue sarcomas. Through collaborative efforts, the Foundation aims to accelerate discoveries that lead to more effective treatments and, ultimately, cures.

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    Recent posts

    • A woman with shoulder-length brown hair and a yellow top smiles softly indoors, with sunlight streaming through large windows covered by bamboo blinds and white curtains in the background.
      Synovial Sarcoma Foundation Welcomes Julie Kramer as Community Engagement & Partnerships Manager
    • A scientist wearing protective clothing, a mask, and safety glasses looks through a microscope in a laboratory setting, with a pen in hand and focused on her research.
      Arizona Pioneers New Immune Therapy for Synovial Sarcoma Treatment
    • A scientist wearing blue gloves holds a flask with blue liquid in a laboratory, surrounded by various glassware and a microscope in the background.
      Revolutionary Insights Unveiled in Latest Synovial Sarcoma Research

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    awareness biotech advancements Black Flag Racing Brigham and Women’s Hospital Callan Spence Cancer Research Chase Spence Chas Spence CHOP Community Engagement & Partnerships Manager Conference Cure Dr. Rachel Hurly Dr. Ted Laetsch Dr. Theodore W. Laetsch fibroblast fibroblast epigenome grant ground breaking immune-cell therapy innovate treaments JAMA Internal Medicine Julie Kramer Nathan Imperiale National Tumor Board Nature Communications patient advocates patient support Pediatric Oncology Penn Medicine Penn Medicine Synovial Sarcoma Foundation Protein-Blocking Drugs Rare Cancer rare disease research Sarcoma SUMO2 inhibitors Synovial Sarcoma Synovial Sarcoma Foundation synovial sarcoma survivor synovial sarcoma treatment TAK-981 TECELRA

    Related posts

    A woman with shoulder-length brown hair and a yellow top smiles softly indoors, with sunlight streaming through large windows covered by bamboo blinds and white curtains in the background.
    Latest News

    Synovial Sarcoma Foundation Welcomes Julie Kramer as Community Engagement & Partnerships Manager

    December 12, 2025 joshs Comments Off on Synovial Sarcoma Foundation Welcomes Julie Kramer as Community Engagement & Partnerships Manager

    Current Patient to Drive Relationships and Support for the Synovial Sarcoma Community [Philadelphia, PA] – 12/12/25 – The Synovial Sarcoma Foundation (SSF) is thrilled to announce the appointment of Julie Kramer as our new Community Engagement & Partnerships Manager. With a wealth of experience in advocacy and nonprofit communications, and as a survivor of synovial […]

    A scientist wearing protective clothing, a mask, and safety glasses looks through a microscope in a laboratory setting, with a pen in hand and focused on her research.
    Research, Uncategorized

    Arizona Pioneers New Immune Therapy for Synovial Sarcoma Treatment

    December 12, 2025 joshs Comments Off on Arizona Pioneers New Immune Therapy for Synovial Sarcoma Treatment

    In a groundbreaking advancement in cancer treatment, a patient with synovial sarcoma in Arizona has become the first in the state to receive a cutting-edge immune-cell therapy, TECELRA, at the HonorHealth Research Institute in Scottsdale. Synovial sarcoma is a rare soft-tissue cancer that primarily affects large joints in the arms and legs, though it can […]

    A scientist wearing blue gloves holds a flask with blue liquid in a laboratory, surrounded by various glassware and a microscope in the background.
    Research

    Revolutionary Insights Unveiled in Latest Synovial Sarcoma Research

    December 4, 2025 joshs Comments Off on Revolutionary Insights Unveiled in Latest Synovial Sarcoma Research

    A landmark study just published in Nature Communications finally pinpointed the exact “cell of origin” for synovial sarcoma — a rare, primitive fibroblast that still carries embryonic markers (Hic1⁺ Pdgfra⁺ Lgr5⁺). Breaking 2025 Research: Read the entire article here. Learn more about our world-renowned registry efforts here.

    The Synovial Sarcoma Foundation is a registered 501(c)(3) nonprofit organization. Tax ID number is 33-4027591. Contributions to the Synovial Sarcoma Foundation are tax-deductible to the extent permitted by law.

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