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    CHOP, Development, Dr. Theodore Laetsch, Research

    Synovial Sarcoma Foundation Celebrates Groundbreaking Achievement by Rachel Dr. Hurly

    June 3, 2025 joshs Comments Off on Synovial Sarcoma Foundation Celebrates Groundbreaking Achievement by Rachel Dr. Hurly
    Close-up of the objective lenses of a microscope, showing three metal lenses labeled with magnification levels above a microscope stage—a vital tool in research supported by the Synovial Sarcoma Foundation.

    Dr. Hurly’s Innovative Work Aims at Improving Therapeutic Options for Patients with Synovial Sarcoma

    Philadelphia, PA — The Synovial Sarcoma Foundation is proud to announce a significant milestone: Dr. Rachel Hurly, a dedicated pediatric oncology fellow from the Children’s Hospital of Philadelphia (CHOP), has been honored with the prestigious American Society of Clinical Oncology (ASCO) Young Investigator Award. Dr. Hurly conducts her research under the mentorship of Dr. Ted Laetsch at the Haldor Laboratory at the University of Pennsylvania, with support from the Synovial Sarcoma Foundation.

    Dr. Hurly’s project focuses on the tumor microenvironment (TME) and its role in enabling or hindering the effectiveness of immunotherapy, specifically investigating the modulation of the TME through the inhibition of retinaldehyde dehydrogenase (RALDH). Early findings suggest that targeting RALDH could promote immune responses against the tumor and enhance the efficacy of existing immunotherapies.

    Chas Spence, Executive Director and Founder of the Synovial Sarcoma Foundation, stated, “Dr. Hurly’s research holds tremendous promise for advancing our understanding of how to manipulate the tumor microenvironment to make immunotherapies more effective for children with synovial sarcoma. Her dedication and innovative approach are truly inspiring.”

    Spence continued, “Our family’s journey with our son Callan’s diagnosis motivated us to become lifelong advocates for synovial sarcoma research. Dr. Hurly’s research and her strong foundation will help propel these efforts forward.”

    The Foundation acknowledges the significant importance of this research, which has the potential to revolutionize the treatment landscape for pediatric sarcoma. The project’s preliminary data highlights promising avenues for future therapeutic development, aiming to improve survival rates and quality of life for young patients.

    “This recognition not only underscores the significance of Dr. Hurly’s research but also emphasizes the vital role that collaborative efforts and dedicated funding play in tackling rare cancers,” added Spence. “We remain committed to supporting groundbreaking research that offers hope and new possibilities for children afflicted by synovial sarcoma and other pediatric cancers.”

    The Synovial Sarcoma Foundation extends its congratulations to Dr. Hurly and her team and remains steadfast in its mission to fund innovative research, foster collaboration, and improve outcomes for pediatric sarcoma patients worldwide.

    About the Synovial Sarcoma Foundation
    The Synovial Sarcoma Foundation is dedicated to funding research, supporting patients and families, and advancing the understanding of synovial sarcoma and related soft tissue sarcomas. Through collaborative efforts, the Foundation aims to accelerate discoveries that lead to more effective treatments and, ultimately, cures.

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    • Latest News (2)
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    Recent posts

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      Rise in Early-Onset Cancers: More Diagnoses, Not Always More Disease
    • A smiling man in a gray suit, light blue shirt, and red tie poses for a professional headshot against a brown, softly blurred background.
      Dr. Theodore W. Laetsch, Synovial Sarcoma Foundation Board Member, Receives $1 Million Grant to Advance Rare Tumor Studies
    • A stethoscope and a blue pen resting on top of a medical chart with patient information and handwritten notes.
      Innovative Approach Shows Promise Against Synovial Sarcoma Using Protein-Blocking Drugs

    Tags

    awareness biotech advancements Black Flag Racing Brigham and Women’s Hospital Callan Spence Cancer Research Chase Spence Chas Spence CHOP Conference Cure Dr. Rachel Hurly Dr. Ted Laetsch Dr. Theodore W. Laetsch grant innovate treaments JAMA Internal Medicine Nathan Imperiale National Tumor Board patient advocates patient support Pediatric Oncology Penn Medicine Penn Medicine Synovial Sarcoma Foundation Protein-Blocking Drugs Rare Cancer rare disease research Sarcoma SUMO2 inhibitors Synovial Sarcoma Synovial Sarcoma Foundation TAK-981

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    Research, Education, Synovial Sarcoma Registry

    Rise in Early-Onset Cancers: More Diagnoses, Not Always More Disease

    October 3, 2025 nathani Comments Off on Rise in Early-Onset Cancers: More Diagnoses, Not Always More Disease

    Not every detected cancer is clinically meaningful. For younger patients, especially, this can mean confronting a diagnosis that may never progress but still carries psychological and treatment burdens.

    A smiling man in a gray suit, light blue shirt, and red tie poses for a professional headshot against a brown, softly blurred background.
    CHOP, Dr. Theodore Laetsch

    Dr. Theodore W. Laetsch, Synovial Sarcoma Foundation Board Member, Receives $1 Million Grant to Advance Rare Tumor Studies

    September 29, 2025 joshs Comments Off on Dr. Theodore W. Laetsch, Synovial Sarcoma Foundation Board Member, Receives $1 Million Grant to Advance Rare Tumor Studies

    The Synovial Sarcoma Foundation is pleased to highlight a significant milestone at the Children’s Hospital of Philadelphia (CHOP), where pediatric oncologist and Synovial Sarcoma Foundation Board Member, Dr. Theodore W. Laetsch, has been awarded a prestigious $1 million multi-year grant from the National Cancer Institute (NCI). This funding aims to accelerate research and treatment development […]

    A stethoscope and a blue pen resting on top of a medical chart with patient information and handwritten notes.
    Latest News, Research

    Innovative Approach Shows Promise Against Synovial Sarcoma Using Protein-Blocking Drugs

    September 11, 2025 joshs Comments Off on Innovative Approach Shows Promise Against Synovial Sarcoma Using Protein-Blocking Drugs

    The Synovial Sarcoma Foundation is dedicated to supporting cutting-edge research that advances treatment options for this rare and aggressive cancer. Recent findings published in The EMBO Journal highlight a promising new strategy: using drug blockers to target a problematic protein involved in synovial sarcoma’s genetics. Synovial sarcoma primarily develops in soft tissues such as muscles […]

    The Synovial Sarcoma Foundation is a registered 501(c)(3) nonprofit organization. Tax ID number is 33-4027591. Contributions to the Synovial Sarcoma Foundation are tax-deductible to the extent permitted by law.

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