Evaluation of Abenacianine (VGT-309) to Identify Cancer in PatientsUndergoing Surgery for Lung Cancer (VISUALIZE-2)
Trial ID: NCT07499674
Phase: Phase 3
Status: Recruiting
Last Update Posted: May 2026
Eligibility: Adults aged 18 and older who are scheduled for surgical resection of a lung lesion or mass with diagnostic or curative intent and are eligible for the planned surgery.
Overview: This Phase 3 trial, sponsored by Vergent Bioscience, Inc., evaluates abenacianine (VGT-309), an investigational fluorescent imaging agent that is administered intravenously 12 to 96 hours before lung surgery. During surgery, near-infrared (NIR) imaging is used to activate the agent, causing tumor cells to “light up” in real time and helping surgeons identify cancer lesions that may not be visible through standard surgical techniques. The study compares standard surgery alone against surgery enhanced with NIR imaging to determine whether the approach improves tumor detection and surgical outcomes. While not a synovial sarcoma-specific trial, this study is relevant to patients with synovial sarcoma who have developed lung metastases and are undergoing surgical resection.
Preliminary Effectiveness: Earlier research suggests tumor-targeted fluorescent imaging may help detect cancer lesions not visible through standard methods. This Phase 3 study aims to confirm whether this approach improves detection and surgical outcomes. No results have been posted to ClinicalTrials.gov at this time.
Study Contact: Vergent Bioscience, Inc.
- Brian York: byork@vergentbio.com / 978-882-1403
- Eric Bensen, PhD: ebensen@vergentbio.com / 952-479-7496
Treatment Centers: USA, Australia
