Name: Taylor Duvall
Primary Tumor Location(s): Extremities, Other
Metastasis or Recurrence Location(s): Lungs, Lymph Nodes
Surgery(s): Amputation, Lymphadenectomy, Thoracotomy, Tumor Resection
Chemotherapy: Ifosfamide (single-agent), AIM (Doxorubicin & Ifosfamide), Other
Radiation: Yes
Targeted Therapies & Trials: Clinical Trial, Targeted Therapy: Votrient (Pazopanib)
Treatment Center(s): Johns Hopkins Hospital (Baltimore, MD), National Institutes of Health (Bethesda, MD)
Current Status: Treatment Ongoing
Profile Narrative: Taylor’s diagnosis followed years of misattributed symptoms. What began as chronic foot pain was initially diagnosed as plantar fasciitis, supported by imaging that showed bone spurs. For nearly two years, custom insoles seemed to manage her discomfort. In late 2021, however, Taylor noticed a growing mass on her left foot. After sudden swelling and an MRI, a 5.3 cm tumor was discovered. A biopsy confirmed synovial sarcoma just days before Christmas. A PET scan revealed lung nodules, making her Stage IV at diagnosis. Living in central Maryland allowed Taylor access to multiple sarcoma centers, and after seeking several opinions, she continued care at Johns Hopkins. She underwent six cycles of AIM chemotherapy followed by high-dose ifosfamide. While her lung tumors responded, the primary tumor in her foot continued to grow. In September 2022, Taylor made the difficult decision to undergo a below knee amputation. Soon after, her lung disease recurred, leading to targeted therapy with Votrient. When progression occurred again, Taylor qualified for a T cell therapy clinical trial at the NIH. While part of her disease responded, new growth required further treatment, including surgery, additional chemotherapy, and radiation. Today, Taylor remains on Votrient with ongoing disease control. Throughout treatment, she completed her master’s degree, remained employed, and married her longtime partner, who proposed on the very day they learned her cancer was Stage IV. Taylor emphasizes the importance of specialized sarcoma care, mental health support, and finding ways to live fully between treatments.
